Sita Bio is decoding the fi
We combine endometrial phenotyping and molecular state mapping with human-relevant models of the womb to test mechanisms and prioritise interventions for embryo implantation and miscarriage.
Early pregnancy loss is heterogeneous
Many patients experience failed implantation or early loss with limited mechanistic explanation. Progress is constrained by limited access to human biology and a lack of controlled systems that connect clinical observations to testable mechanisms.
A mechanism-first platform
Define
Integrate clinical context with deep endometrial characterisation to define biological states underlying early pregnancy failure.
Derive
Derive dynamic, perturbable human models of implantation to functionally recreate the maternal–fetal interface.
Discover
Discover protocols and interventions, prioritising therapeutic candidates for implantation failure and recurrent miscarriage.
We build functional models of implantation
Implantation is a coordinated interplay between decidua/stroma, immune signalling, and trophoblast invasion. We recreate these interactions with hormone-responsive epithelium, stromal ECM, perfusable vasculature, and immune elements—enabling functional testing to guide protocols and identify therapeutic opportunities.
Perfusable uterine microvasculature
From uncertainty to targeted care.
Implantation failure is not one problem. It reflects multiple underlying biological states. We give patients clearer insight into what may be driving failure, and help clinics tailor protocols and adjunct choices with stronger mechanistic rationale. Our long-term goal is simple: make the first transfer the right one.
Clinics
Sharper stratification, more confident protocol decisions
Patients
Clearer explanations, more targeted next steps
Future
Precision protocols for conception and new therapies for early pregnancy loss
Ready to collaborate?
Whether you're a clinical partner, researcher, investor, or a patient facing repeated implantation failures interested in participating in our clinical trials, we'd love to explore how we can work together to advance reproductive medicine.